Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com

Crestor may cause rhabdomyolysis and kidney failure. Find a Crestor lawyer at Monheit.com

  The problem Crestor presents for the FDA

Crestor may cause rhabdomyolysis and kidney failure. Find a Crestor lawyer at Monheit.com
Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com Crestor may cause rhabdomyolysis and kidney failure. Find a Crestor lawyer at Monheit.com
Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com
Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com"

Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com

Crestor

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com Do I have a Crestor case?



 

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com What is Crestor?

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com What is the problem?

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com Who is responsible?

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com What is being done?

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com What can you do?

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com FAQs

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com Breaking news

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com Crestor Web Resources

Crestor life-threatening side effects include rhabdomyolysis, kidney failure, myoglobinuria. Contact Monheit.com Medical information

 

Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com
Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com Do you have a Crestor lawsuit? Get a free Crestor consultation at Monheit.com Do you suffer from kidney damage? Talk to an expert Crestor lawyer at monheit.com
What is the Problem with Crestor?

 

So long as Crestor is taken according the proper prescribing instructions, there is nothing wrong with the product, according to counsel for AstraZeneca. In a letter to this firm, they believe, and we agree, that patients should not be discouraged from following the advice of their physicians.

We agree with AstraZeneca's attorney that patients should follow the "advice of their physicians that they use FDA-approved therapies." Further, according to AstraZeneca's attorney "[f]or persons taking Crestor on their physicians' advice," they should not "stop taking the drug without the knowledge of their physician" as this "may result in serious complications and injury." We agree with AstraZeneca that it is important that the medical community maintain the "ability to convey accurate information to patients and to provide needed professional medical assistance." Please consult your physician regarding any questions or concerns that you have regarding medications and medical treatment.


However, we believe that there is a problem, such as we have seen recently in the news with Vioxx, in that the FDA has not always been a good regulator in recent years. This may leave people at risk of taking drugs that may later turn out to be dangerous. For example, on March 4, 2004, Public Citizen called on the U.S. Food and Drug Administration (FDA) to immediately remove the cholesterol-lowering drug rosuvastatin from the market. The drug, marketed by AstraZeneca as Crestor, has been linked to cases of life-threatening muscle damage and kidney failure or damage.

The problem according to another press release from Public Citizen, is that "[i]t becomes clearer by the day that this drug is uniquely toxic without offering any unique benefit, and that it must be removed from the market". However, according to counsel for AstraZeneca, in a letter to this firm, "studies have shown that Crestor offers features unique among the currently marketed statins, including: (1) the greatest efficacy for lowering serum LDL cholesterol; and (2) significant increases in beneficial HDL-C."
 

And, the problem, in general, with pharmaceutical products and politics is that the pharmaceutical industry paid lobbyists give astronomical sums of money to presidential and other political candidates. Just as many of these pharmaceutical manufacturers complain of the monies given by Trial Lawyers to political candidates in order to help maintain access to the civil justice system for individuals who have been harmed by unsafe drugs, one can only wonder what the pharmaceutical lobbyists expect as a result of making their large political contributions.

There are currently six statin drugs on the market:

  • atorvastatin (Lipitor)

  • fluvastatin (Lescol)

  • lovastatin (Mevacor)

  • pravastatin (Pravachol)

  • simvastatin (Zocor)

  • rosuvastatin (Crestor)

A seventh statin, cerivastatin (Baycol) was removed from the market in 2001 because of adverse reactions and serious side effects, including rhabdomyolysis.

Statins work by reducing production of cholesterol in the liver and by increasing the ability of the liver to remove LDL (bad) cholesterol from the blood. Statins reduce the level of LDL cholesterol in the blood and can reduce triglyceride levels and increase levels of HDL (good) cholesterol.

The newest statin, rosuvastatin (Crestor) has been marketed as a "super-statin" because AstraZeneca claims it reduces LDL cholesterol to a greater degree than the other approved statin drugs.

The approval of rosuvastatin (Crestor) is controversial because it follows the recall of Bayer’s cerivastatin (Baycol) which was also a super-statin. In 2001, Baycol was removed from the market because it caused life threatening side effects like rhabdomyolysis, a fatal muscle disorder. Side effects were reported with Crestor that appeared reminiscent of the Baycol experience. Cases of rhabdomyolysis were seen with Crestor during drug trials, particularly with the 80 mg. dose.

Crestor won FDA approval in August 2003 in 5, 10, 20, and 40 mg. doses, but not the 80 mg. dosage. In recent months there have been reports of serious side effects resulting from use of Crestor.

The FDA already has records of seven patients with rhabdomyolysis, including, according to Public Citizen, a 39-year-old American who died after using a 20-mg. dose, and a second death from an unspecified country. However, according to counsel for AstraZeneca, in a letter to this firm, "[a]lthough an adverse event report regarding the death of a 39 year-old woman came to AstraZeneca (and was in turn submitted to the FDA), subsequent investigation revealed that autopsy records for this patient established that she died of an actue myocardial infarction. In other words, the patient's death had nothing to do with Crestor."

Four patients with acute kidney failure, including a 79-year-old American man who died plus five additional patients with kidney damage. Crestor interacted dangerously with the blood-thinner Coumadin, commonly used by heart-disease patients; one Crestor-Coumadin interaction resulted in a hemorrhage. Who knows how many cases have not yet been reported to the FDA. Some studies show that only one-tenth of the actual cases are reported to the FDA.

The fact that so few patients on the 20 or 40 mg. doses took the drug for a sufficient period of time to have had a chance to develop rhabdomyolysis seems to have imparted a false sense of security about the safety of these doses concerning muscle toxicity. It is certainly possible that the FDA will require that Crestor be removed from the market after further damage to patients occurs.

 

Do I have a Crestor lawsuit?
Do you have a Crestor lawsuit? Do you have a case for a lawsuit against the manufacturer of Crestor? Please complete our no obligation, free consultation form. Experts and lawyers familiar with Crestor lawsuits are standing by to assist you.

First Name:
Last Name:
E-mail Address:
Day Phone: () - ext.
Other Phone: () - ext.
Address:
City:
State:
Zipcode:


Crestor Lawsuit Personal injury case facts

Has a doctor said that you have a medical condition caused by Crestor?
Yes
No
If yes, please indicate which disease(s) the doctor diagnosed; check all that apply:
Rhabdomyolysis
Hemorrhage
Drug induced hepatitis
Myoglobinuria
Acute renal failure
Stevens Johnson Syndrome
Other
Have any of the following problems occurred while taking Crestor? If yes, please indicate which symptom(s) you have had; check all that apply:
Muscle Pain
Dark Urination
Liver Problems
Malaise
General Weakness
Nausea
Skin Blisters or Ulcers
What date was the initial diagnosis?
Date of Birth?
Have you already filed a lawsuit concerning your Crestor-related disease?
Yes
No
What dosage of Crestor was prescribed?
Were you taking Lopid (gemfibrozil) at the same time you were taking Crestor?
Yes
No
Were you taking Coumadin at the same time you were taking Crestor?
Yes
No
Was a CPK test performed?
Yes
No
If so, what were the CPK test Results:


Crestor Lawsuit Wrongful Death Case Facts

Was a Crestor-related disease possibly involved with the death of a family member or someone else you know?
Yes
No
What was the date of death?


Additional Information about your potential Crestor Lawsuit:

Is there any additional information you would like to include? Please enter any additional information about this claim, as well as any comments or questions you may have, in the following space:
Philadelphia Lawyers - Pennsylvania Lawsuits at Monheit Law

Law Offices of Michael Monheit 1368 Barrowdale Road  Rydal, PA  19046
Call Us Toll Free: 866-761-1385  P: 215-840-6573  E: Michael@Monheit.com