Study Demonstrated Long-Term Treatment with Zyprexa(R) Reduced Violent Behavior in People with Schizophrenia Compared to Risperidone

Contact: Michael Monheit, Esquire, Monheit Law, PC
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In this non-randomized prospective study, 124 adults with schizophrenia- spectrum disorders receiving services in public-sector mental health systems in North Carolina were followed for three years. Rates of violence among people who were initiated on Zyprexa (N=59) were compared with people who were initiated on risperidone (N=65) at six-month intervals. -- Remaining on Zyprexa for one year or more significantly lowered the risk of violent behavior - No significant change in violence risk was found for subjects remaining on risperidone for one year or more -- More violence-prone patients were initially switched to Zyprexa -- The reduction in violent behavior associated with Zyprexa treatment was attributed to higher rates of medication adherence