What are Trasylol side effects? What is aprotinin?
In 1991, 265,000 coronary bypass graft operations were performed to replace
diseased blood vessels. Excessive bleeding is a frequent complication of this
surgery. Two placebo controlled clinical trials conducted in the United States
demonstrated that aprotinin effectively reduced blood loss and decreased the
need for transfusions. In one study, 42 percent of patients treated with
aprotinin needed at least one unit of blood, compared to 77 percent who did not
receive the drug. The second study showed similar results. Fewer transfusions
mean a much lower risk of infection or possible adverse reactions to the blood.
Trasylol was studied for use mainly in heart surgery because the circulation of
the blood outside the body for this surgery increases the likelihood of
excessive bleeding during and after surgery particularly for patients with rare
blood types or in other cases when access to blood is limited.
Using Trasylol should be reserved for high risk
patients only because severe allergic reactions can result from using it more
than once in a patient. Kidney toxicity was also a problem in some patients
during the clinical trials.
What are the side effects from using Trasylol?
Side effects that you should report to your health care professional as soon as
possible:
difficulty breathing or shortness of breath
fast heart beat
nausea and vomiting
skin rash, irritation or inflammation
sudden or severe pain in the chest, legs, head, or groin
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