PPA (Phenylpropanolamine)

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What is PPA (Phenylpropanolamine)?

 

PPA (Phenylpropanolamine), (pronounced "fen-el-pro-pa-nol-a-mine") was at one time a popular ingredient in prescription and over-the-counter medications and diet pills. Although it has since been ordered off the shelves by the FDA, several products containing PPA may still be found in the personal medicine cabinets of many Americans. The product was used primarily as a nasal decongestant to relieve stuffy nose, sinus congestion, and allergy symptoms. It may also be found in older over-the-counter weight loss products that are used to control appetite. Products containing PPA may be identified by looking for "PPA (Phenylpropanolamine)" in the list of active ingredients on the label. This chemical is commonly referred to as PPA.

 

PPA was used in prescription medications and over-the-counter medications for many years. On May 11, 2000, FDA received results of a study conducted by scientists at Yale University School of Medicine that showed an increased risk of hemorrhagic stroke (bleeding of the brain) in people who were using products that contained PPA. Although the risk of hemorrhagic stroke is very low, FDA had significant concerns because of the seriousness of a stroke and the inability to predict who is at risk. The FDA has concluded that the risks of using PPA outweigh the benefits and has recommended that consumers no longer use products containing PPA.

 

The FDA originally asked firms that sold pharmaceutical or drug products containing PPA (Phenylpropanolamine) to voluntarily discontinue selling them. Eventually, the FDA ordered the removal of all products containing PPA from the shelves of drug stores and other retailers. The FDA has also taken steps to alert consumers to the risks associated with the use of products containing PPA (Phenylpropanolamine). PPA is now only available by prescription in a limited number of products.


What products contain PPA?

Since PPA was banned by the FDA, newer over-the-counter medications do not contain the ingredient. Products that contained PPA were either reformulated or replaced with some other product.

At one time, there were approximately 400 products that contained PPA.  Many of these medications and diet products are still being used by people who purchased prior to the FDA ban.

 

All of the products listed below at one time contained PPA:

 

12-Hour Cold

Alamine 

Alka-Seltzer Plus Cold

Alka-Seltzer Plus Maximum

Strength Sinus Allergy

Alka-Seltzer Plus Maximum Strength Sinus Allergy Medicine                              

Alka-Seltzer Plus Nighttime Cold

Alumadrine

Amaril D 

Ami-Tex LA

Anatuss

Anatuss with Codeine 

A.R.M. Maximum Strength

BC Cold Powder

BC Cold Powder Non-Drowsy

Banex

Banex Liquid  

Banex-LA 

Bayaminic Expectorant

Bayaminicol

Baycomine

Baycomine Pediatric

Bayer Cough Syrup

Bayer Cough Syrup for Children

Biphetane DC Cough Syrup

BQ Cold    

Bromanate DC Cough Syrup

Bromatap                

Bromatapp              

Bromophen T.D.  

Bromphen DC w/Codeine Cough 

Caldomine-DH Forte               

Caldomine-DH Pediatric

Cheracol Plus         

Chexit                  

Chlor-Rest               

Chlor-Trimetron Sinus Caplets

Chlor-Tripolon Decongestant

Codamine   

    

Codamine Pediatric            

Codegest Expectorant             

Codimal Expectorant           

Comtrex Multi-Symptom              

  Cold Reliever    

Condrin-LA          

Conex                   

Conex D.A.                    

Conex Plus                  

Conex w/Codeine Liquid              

Congesprin for Children

Liquid Cold Medicine                   

Contac Jr. Children's Cold Medicine                  

Contac 12-Hour     

Contac Maximum Strength 12-Hour

Contac Maximum Strength 12-HourCaplets                    

Cophene-S                    

Cophene-X                        

Cophene-XP                 

Coricidin Cough                  

Coricidin D        

Coricidin D Decongestant 

Coricidin D

Medilets  

Coricidin Demilets                 

Coricidin Maximum Strength Sinus Headache                        

Corsym                             

Dapacin Cold                     

Decongestabs                

Dehist      

Demazin                           

Demazin Repetabs 

Despec 

Dilotab                           

Dimaphen S.A. 

Dimetane Expectorant 

Dimetane Expectorant-C  

Dimetane Expectorant-DC  

Dimetane-DC Cough  

Dimetapp       

Dimetapp-A        

Dimetapp-A Pediatric  

Dimetapp-DM    

Dimetapp with Codeine  

Dimetapp Extentabs  

Dimetapp Maximum Strength Formula                    

Dimetapp Oral Infant Drops

Dimetapp Plus Caplets            

Dorcol DM                           

Drinophen

Dristan                        

Drize             

Duadacin

Dura-Vent                           

Dura-Vent/A

Efficol Cough Whip (Cough Relief Suppressant / Decongestant)   

Efficol Cough Whip (Cough

  Suppressant/Decongestant/ 

  Antihistamine)   

Efficol Whip

Entex              

Entex LA     

Entex Liquid                     

Extreme Cold Formula Caplets

Flogesic                                   

Genamin                                 

Genatap     

Gencold                           

Genex                                     

Gentab-LA          

Guaipax           

Halls Mentho-Lyptus   

Halls Mentho-Lyptus           

  Decongestant Cough 

  Formula                          

Head & Chest                     

Histabid Duracaps                      

Histalet Forte                    

Histamic                               

Hista-Vadrin    

Histosal                               

Hold (Children's Formula)            

Hycomine                              

Hycomine Pediatric  

Hydromine               

Hydromine Pediatric    

Hydrophen Veltap

Kiddy Koff 

Kolephrin/DM    

Kolephrin NN Liquid

Kophane  

Kophane Cough and Cold Formula

Lanatuss Expectorant  

Medatussin Plus    

Myhydromine    

Myhydromine Pediatric  

Myminic 

Myphetane DC Cough 

Myphetapp      

Naldecon 

Naldecon Pediatric   

Naldecon-CX Adult Liquid

Naldecon-DX Adult Liquid 

Naldecon-DX Children's Syrup

Naldecon-DX Pediatric Drops

Naldecon-EX

Naldelate Caplets   

Naldelate Pediatric Syrup

Nalgest  

Nasahist Formula

New-Decongest    

New-Decongest Pediatric Syrup

Nolamine

Nolex LA

Noraminic

Norel Plus

Normatane

Normatane DC

Oragest S.R.    

Oraminic Spancaps

Ornade       

Ornade A.F.  

Ornade-DM 

Ornade-DM 10

Ornade-DM 15 

Ornade-DM 30   

Ornade Expectorant  

Orthoxicol Cough

Panadyl       

Par Decon

Pertussin AM   

Phanadex   

PhenAPAP No. 2

Phenate T.D. 

Phentox Compound 

Phenylfenesin L.A.

Poly-Histine-CS  

Poly-Histine-D  

Poly-Histine-D Ped

Poly-Histine-DM 

Prominic Expectorant

Prominicol Cough

Pyrroxate  

Remcol Cold  

Rentamine  

Resaid S.R. 

Rescaps-D S.R.   

Respinol-G 

Respinol LA

Rhinocaps  

Rhinolar-EX

Rhinolar-EX 12  

Robitussin-CF  

Ru-Tuss II 

Ru-Tuss w/Hydrocodone Liquid 

Rymed

Rymed Liquid

Saleto-CF 

Saleto-D        

Sinapils 

Sine-Off Sinus Medicine

Sinubid 

Sinucon Pediatric Drops 

Sinulin 

Sinutab SA  

Snaplets-D 

Snaplets-DM 

Snaplets-EX 

Snaplets-Multi  

St. Joseph Cold Tablets for Children      

Stamoist LA

Statuss Green 

Syracol Liquid  

Tamine S.R.    

Tavist-D 

T-Koff  

Triaminic 

Triaminic Allergy  

Triaminic Chewables 

Triaminic Cold Liquigels

Triaminic-DM Cough

Triaminic-DM Expectorant   

Triaminic Expectorant  

Triaminic Expectorant DH  

Triaminic Expectorant w/Codeine

Triaminic Oral Infant Drops 

Triaminic TR

Triaminicin 

Triaminicin w/Codeine

Triaminicol DM 

Tricodene Forte

Tricodene NN  

Tricodene NN Pediatric Medication  

Tricodene Pediatric  

 

Trind

Trind DM Liquid

Tri-Nefrin Extra Strength

Tripalgen Cold

Tri-Phen-Chlor

Tri-Phen-Chlor T.D. 

Triphenyl     

Triphenyl Expectorant

Triphenyl T.D.

Tusquelin    

Tuss-Ade   

Tussagesic   

Tuss Allergine Modified T.D.     

Tussaminic C Forte      

Tussaminic C Pediatric    

Tussaminic DH Forte 

Tussaminic DH Pediatric  

Tussanil DH Tablets 

Tussogest   

Tuss-Ornade Liquid  

Tuss-Ornade Spansules 

ULR-LA  

Utex-S.R.   

Vasominic T.D.   

 


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