Use of Paroxetine in First Trimester of Pregnancy May Have a Small Increased Risk of Birth Defects, Compared to Other Antidepressants
October 9, 2005 18:41

GlaxoSmithKline Inc., following discussions with Health Canada, is informing patients of new safety information regarding the use of paroxetine during the first trimester of pregnancy. Paroxetine is used for relieving the symptoms of depression and anxiety. As a result of this new safety information, GlaxoSmithKline recommends the following:

* As per the current Consumer Information for paroxetine, women who are currently taking paroxetine and are pregnant, or planning on becoming pregnant, should discuss with their doctor the potential risks and benefits of using paroxetine therapy during pregnancy.

* Doctors have been advised of this new safety information, and are encouraged to discuss the risks and benefits of using paroxetine during pregnancy with their patients.

* Due to the risk of discontinuation symptoms, it is very important that patients do NOT stop taking paroxetine without first consulting with their doctor.